Motif ID: HOX{A6,A7,B6,B7}.p2

Z-value: 1.760


Transcription factors associated with HOX{A6,A7,B6,B7}.p2:

Gene SymbolEntrez IDGene Name
HOXA6 3203 homeobox A6
HOXA7 3204 homeobox A7
HOXB6 3216 homeobox B6
HOXB7 3217 homeobox B7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXB7hg19_v1_chr17_-_46688279_466883500.632.0e-09Click!
HOXB6hg19_v1_chr17_-_46682333_466823560.262.3e-02Click!
HOXA7hg19_v1_chr7_-_27196163_271963280.084.9e-01Click!
HOXA6hg19_v1_chr7_-_27187367_27187392-0.065.9e-01Click!


Activity profile for motif HOX{A6,A7,B6,B7}.p2.

activity profile for motif HOX{A6,A7,B6,B7}.p2


Sorted Z-values histogram for motif HOX{A6,A7,B6,B7}.p2

Sorted Z-values for motif HOX{A6,A7,B6,B7}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A6,A7,B6,B7}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_114066554 20.907 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr12_-_28124915 20.680 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr8_-_82395401 19.052 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr7_+_28452143 18.918 NM_182898
CREB5
cAMP responsive element binding protein 5
chr7_+_107110501 18.540 NM_005295
GPR22
G protein-coupled receptor 22
chr5_+_147582338 17.537 NM_001195290
NM_205841
SPINK6

serine peptidase inhibitor, Kazal type 6

chr5_-_88119604 16.813 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr18_+_28898051 16.761 NM_001942
DSG1
desmoglein 1
chr7_-_25268057 15.704 NM_022150
NPVF
neuropeptide VF precursor
chr8_+_104831415 13.721 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr7_+_114055048 13.645 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr2_-_99871569 13.146 NM_175735
LYG2
lysozyme G-like 2
chr2_+_166428845 13.092 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr17_-_39093671 12.935 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr11_+_99426872 12.876 NM_175566
CNTN5
contactin 5
chr17_-_39092714 12.665 KRT23
keratin 23 (histone deacetylase inducible)
chr7_+_114055234 12.366 FOXP2
forkhead box P2
chr7_-_14025826 11.778 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr7_-_115670811 11.491 TFEC
transcription factor EC
chr11_+_113775517 11.435 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr7_+_114055171 11.351 FOXP2
forkhead box P2
chr2_+_162272619 11.176 NM_006593
TBR1
T-box, brain, 1
chr12_-_16760935 10.907 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr2_-_176948689 10.880 NM_001080458
EVX2
even-skipped homeobox 2
chr6_+_105404922 10.831 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr5_+_59784004 10.684 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr7_-_115670774 10.630 TFEC
transcription factor EC
chr2_+_182850550 10.607 NM_001080545
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr3_+_2553272 10.214 CNTN4
contactin 4
chr1_+_199996729 10.055 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr10_-_21807120 9.976


chr4_-_116034932 9.912 NM_022569
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr13_-_103719195 9.826 NM_000452
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter family), member 2
chr12_-_89745997 9.817 DUSP6
dual specificity phosphatase 6
chr6_+_12716887 9.660 PHACTR1
phosphatase and actin regulator 1
chr6_+_100054649 9.624 NM_021620
PRDM13
PR domain containing 13
chr13_-_46425756 9.590 NM_198849
SIAH3
seven in absentia homolog 3 (Drosophila)
chr2_+_162272892 9.580 TBR1
T-box, brain, 1
chr12_-_16430618 9.567 NM_001170798
SLC15A5
solute carrier family 15, member 5
chr12_-_89746244 9.354 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr17_-_38859976 9.353 NM_019016
KRT24
keratin 24
chr13_-_86373328 9.336 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr17_-_38978824 9.332 NM_000421
KRT10
keratin 10
chr12_+_20963637 9.221 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr15_+_58430394 9.189 NM_020980
AQP9
aquaporin 9
chr6_+_12717036 9.120 NM_001242648
NM_030948
PHACTR1

phosphatase and actin regulator 1

chr2_+_226265601 9.119 NM_020864
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr1_+_152956563 9.066 NM_001199828
NM_005987
SPRR1A

small proline-rich protein 1A

chr2_+_162272800 8.989 TBR1
T-box, brain, 1
chr7_-_115670828 8.853 NM_001018058
NM_012252
TFEC

transcription factor EC

chr14_-_95236351 8.851 NM_173849
GSC
goosecoid homeobox
chr19_-_51512803 8.831 NM_012315
KLK9
kallikrein-related peptidase 9
chr18_-_56985693 8.831 NM_181654
CPLX4
complexin 4
chr2_+_234826042 8.779 NM_024080
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr12_-_57328044 8.743 NM_148897
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr17_-_46687925 8.733 HOXB7
homeobox B7
chr7_+_28475233 8.669 NM_004904
CREB5
cAMP responsive element binding protein 5
chrX_-_19817907 8.652 NM_001024666
SH3KBP1
SH3-domain kinase binding protein 1
chr22_-_37098620 8.633 NM_006078
CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chrX_-_137821514 8.617 NM_033642
FGF13
fibroblast growth factor 13
chr13_-_36050758 8.613 NM_005584
MAB21L1
mab-21-like 1 (C. elegans)
chrX_-_124097601 8.569 NM_001163278
NM_001163279
NM_014253
ODZ1


odz, odd Oz/ten-m homolog 1 (Drosophila)


chr12_+_89744714 8.561 LOC100131490
uncharacterized LOC100131490
chr4_-_41884568 8.545


chrX_+_28605558 8.541 NM_014271
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr3_-_64211111 8.516 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr12_-_45307710 8.481 NM_001145110
NELL2
NEL-like 2 (chicken)
chr21_-_31538970 8.476 NM_012131
CLDN17
claudin 17
chr1_+_50569581 8.427 NM_001144776
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr3_-_71353910 8.408 NM_001244812
FOXP1
forkhead box P1
chr2_-_2334887 8.385 NM_015025
MYT1L
myelin transcription factor 1-like
chr16_-_51185150 8.354 NM_002968
SALL1
sal-like 1 (Drosophila)
chr7_+_28725597 8.301 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr16_+_7382750 8.276 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr18_-_61329113 8.176 NM_006919
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chrX_+_9431314 8.161 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr20_-_7921068 8.106 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chrX_+_91090459 8.089 NM_001168360
NM_001168361
NM_001168362
NM_001168363
PCDH11X



protocadherin 11 X-linked



chr12_+_21525801 8.040 NM_000415
IAPP
islet amyloid polypeptide
chr12_-_89746238 7.981 DUSP6
dual specificity phosphatase 6
chr5_-_88199868 7.965 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr11_-_84634219 7.955 DLG2
discs, large homolog 2 (Drosophila)
chr17_-_46688279 7.923 HOXB7
homeobox B7
chr8_-_87755880 7.882 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chrX_-_19817854 7.880 SH3KBP1
SH3-domain kinase binding protein 1
chr13_+_53602829 7.876 NM_006418
OLFM4
olfactomedin 4
chr6_+_45296053 7.870 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr3_-_167191808 7.756 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr3_+_35721115 7.747 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr6_-_55740387 7.712 BMP5
bone morphogenetic protein 5
chr10_+_11047339 7.695 CELF2
CUGBP, Elav-like family member 2
chr3_-_71294229 7.693 NM_001244814
FOXP1
forkhead box P1
chr6_+_136172802 7.691 NM_018945
PDE7B
phosphodiesterase 7B
chr1_-_216596737 7.511 NM_007123
NM_206933
USH2A

Usher syndrome 2A (autosomal recessive, mild)

chr12_-_53074172 7.471 NM_006121
KRT1
keratin 1
chr8_+_77593506 7.426 NM_024721
ZFHX4
zinc finger homeobox 4
chr9_-_95244750 7.250 NM_001193335
NM_017680
ASPN

asporin

chr15_+_34261088 7.217 NM_012125
CHRM5
cholinergic receptor, muscarinic 5
chr6_-_123957941 7.210 NM_001251987
NM_006073
TRDN

triadin

chr3_-_62359189 7.204 NM_018008
FEZF2
FEZ family zinc finger 2
chr6_-_55740358 7.177 NM_021073
BMP5
bone morphogenetic protein 5
chr18_+_28956739 7.171 NM_001134453
NM_177986
DSG4

desmoglein 4

chr18_+_32173281 7.166 NM_001128175
NM_001198938
NM_001198939
NM_001198940
DTNA



dystrobrevin, alpha



chr9_-_95244634 7.114 ASPN
asporin
chr3_-_54961961 7.046 NM_020678
LRTM1
leucine-rich repeats and transmembrane domains 1
chr4_-_68829143 7.043 NM_001114387
NM_182606
TMPRSS11A

transmembrane protease, serine 11A

chrX_-_18690187 7.042 NM_000330
RS1
retinoschisin 1
chr8_+_77593522 7.033 ZFHX4
zinc finger homeobox 4
chr4_+_88720701 7.003 NM_004967
IBSP
integrin-binding sialoprotein
chr8_+_75736771 6.923 NM_015886
PI15
peptidase inhibitor 15
chr12_-_99548867 6.910 NM_001204067
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr9_-_95166827 6.838 NM_014057
NM_033014
OGN

osteoglycin

chr3_+_2280512 6.837 NM_001206955
CNTN4
contactin 4
chr3_-_114478117 6.832 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr5_-_145252530 6.794 NM_001080516
GRXCR2
glutaredoxin, cysteine rich 2
chr6_-_108145507 6.774 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chrX_-_64196268 6.751 NM_001178033
NM_018684
ZC4H2

zinc finger, C4H2 domain containing

chr1_+_50574601 6.743 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr18_-_3874252 6.726 NM_001242764
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr5_-_134914968 6.715 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr7_+_39017608 6.681 NM_001166018
NM_007252
POU6F2

POU class 6 homeobox 2

chr13_-_84456473 6.678 NM_052910
SLITRK1
SLIT and NTRK-like family, member 1
chr5_+_170736287 6.603 NM_021025
TLX3
T-cell leukemia homeobox 3
chr6_+_153019029 6.595 NM_025107
MYCT1
myc target 1
chr1_+_198608216 6.569 PTPRC
protein tyrosine phosphatase, receptor type, C
chr17_-_10452939 6.555 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chr5_-_76934373 6.548 OTP
orthopedia homeobox
chr12_-_28122884 6.499 NM_198964
NM_198966
PTHLH

parathyroid hormone-like hormone

chr9_+_118916069 6.463 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr21_-_39870303 6.435 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr12_-_14132920 6.412 NM_000834
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr2_-_233641225 6.406 NM_001172416
NM_001172417
NM_002242
KCNJ13


potassium inwardly-rectifying channel, subfamily J, member 13


chr11_-_36619776 6.374 NM_000536
NM_001243785
NM_001243786
RAG2


recombination activating gene 2


chr5_-_88179278 6.374 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr4_-_72649734 6.372 NM_000583
GC
group-specific component (vitamin D binding protein)
chr4_+_15341559 6.342 NM_001135170
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr14_+_76837689 6.310 NM_004452
ESRRB
estrogen-related receptor beta
chr13_-_84456424 6.305 SLITRK1
SLIT and NTRK-like family, member 1
chr3_-_74570262 6.301 NM_020872
CNTN3
contactin 3 (plasmacytoma associated)
chr10_-_118897811 6.274 NM_001112704
NM_199131
VAX1

ventral anterior homeobox 1

chr14_-_101036130 6.257 NM_020836
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr12_-_89745753 6.253 DUSP6
dual specificity phosphatase 6
chr1_+_177140062 6.236 FAM5B
family with sequence similarity 5, member B
chr5_+_60933635 6.179 NM_173667
C5orf64
chromosome 5 open reading frame 64
chr1_+_50574589 6.154 NM_001144774
NM_021952
ELAVL4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr10_+_11047274 6.142 CELF2
CUGBP, Elav-like family member 2
chr4_-_174451356 6.134 NM_021973
HAND2
heart and neural crest derivatives expressed 2
chr4_+_88529680 6.133 NM_014208
DSPP
dentin sialophosphoprotein
chr5_-_76934508 6.108 NM_032109
OTP
orthopedia homeobox
chr2_-_29297126 6.101 NM_001029883
C2orf71
chromosome 2 open reading frame 71
chr9_+_27109138 6.070 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr18_-_31628557 6.066 NM_001198549
NOL4
nucleolar protein 4
chr10_-_50599906 6.055 NM_001080520
DRGX
dorsal root ganglia homeobox
chr2_-_2335080 6.038 MYT1L
myelin transcription factor 1-like
chr8_-_42234562 6.034 NM_014420
DKK4
dickkopf homolog 4 (Xenopus laevis)
chr5_+_161494647 6.022 NM_000816
NM_198903
NM_198904
GABRG2


gamma-aminobutyric acid (GABA) A receptor, gamma 2


chr5_+_36606667 5.962 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_+_80838125 5.904 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr1_-_217250230 5.896 NM_001243507
NM_001243509
ESRRG

estrogen-related receptor gamma

chr21_-_40033617 5.893 NM_001243432
NM_001136154
NM_004449
ERG


v-ets erythroblastosis virus E26 oncogene homolog (avian)


chr6_+_27925018 5.892 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr5_+_36606456 5.888 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr13_-_103054027 5.852 NM_175929
FGF14
fibroblast growth factor 14
chr6_+_54173202 5.846 NM_014464
TINAG
tubulointerstitial nephritis antigen
chr5_-_141993691 5.832 NM_033137
FGF1
fibroblast growth factor 1 (acidic)
chr4_-_57547845 5.824 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr19_-_51522953 5.823 NM_145888
KLK10
kallikrein-related peptidase 10
chr1_-_197036350 5.800 NM_001994
F13B
coagulation factor XIII, B polypeptide
chr3_-_97754147 5.757 NM_001105580
GABRR3
gamma-aminobutyric acid (GABA) receptor, rho 3
chr7_-_37025696 5.731 ELMO1
engulfment and cell motility 1
chr1_-_114429996 5.718 BCL2L15
BCL2-like 15
chr1_+_50571963 5.690 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr18_-_3845295 5.671 NM_001003809
NM_001242765
NM_001242766
DLGAP1


discs, large (Drosophila) homolog-associated protein 1


chr9_-_124989755 5.665 NM_001242334
LHX6
LIM homeobox 6
chr18_-_64271215 5.652 NM_021153
CDH19
cadherin 19, type 2
chr18_+_32073245 5.630 NM_001198945
NM_001392
NM_032975
NM_032979
DTNA



dystrobrevin, alpha



chr16_+_2653350 5.627 LOC652276
potassium channel tetramerisation domain containing 5 pseudogene
chr5_-_131879172 5.608 NM_000879
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr20_+_62795826 5.602 NM_004535
MYT1
myelin transcription factor 1
chr10_+_11207053 5.584 CELF2
CUGBP, Elav-like family member 2
chr17_-_46671322 5.560 HOXB5
homeobox B5
chr20_-_50418946 5.554 NM_020436
SALL4
sal-like 4 (Drosophila)
chr12_-_52946734 5.531 NM_033448
KRT71
keratin 71
chr17_-_39123137 5.525 NM_213656
KRT39
keratin 39
chr4_-_44653657 5.524 NM_182592
YIPF7
Yip1 domain family, member 7
chr11_+_15133969 5.510 NM_001031853
INSC
inscuteable homolog (Drosophila)
chr3_+_132318980 5.498 NM_178445
CCRL1
chemokine (C-C motif) receptor-like 1
chrX_+_115567746 5.447 NM_007231
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr17_-_10421858 5.441 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chrX_-_110513750 5.438 NM_014289
CAPN6
calpain 6
chr14_+_62462540 5.433 NM_031914
SYT16
synaptotagmin XVI
chr16_+_2732475 5.425 NM_018992
KCTD5
potassium channel tetramerisation domain containing 5
chr3_-_114343052 5.405 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_21792815 5.392 NM_024697
ZNF385D
zinc finger protein 385D
chr11_-_84634437 5.367 NM_001364
DLG2
discs, large homolog 2 (Drosophila)
chr7_-_112727778 5.359 GPR85
G protein-coupled receptor 85
chr10_-_69455926 5.331 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr3_+_127641901 5.320 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr12_-_70093064 5.312 NM_032735
BEST3
bestrophin 3
chr3_+_173116243 5.307 NM_014932
NLGN1
neuroligin 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.65 9.66e-38 GO:0032501 multicellular organismal process
1.82 2.84e-25 GO:0048731 system development
1.71 1.50e-24 GO:0007275 multicellular organismal development
1.74 1.98e-23 GO:0048856 anatomical structure development
1.64 1.08e-22 GO:0032502 developmental process
1.97 1.51e-15 GO:0007399 nervous system development
1.87 4.12e-15 GO:0003008 system process
1.82 7.85e-15 GO:0048513 organ development
1.71 5.02e-12 GO:0030154 cell differentiation
1.88 1.34e-11 GO:0050877 neurological system process
1.68 2.39e-11 GO:0048869 cellular developmental process
1.98 6.29e-10 GO:0007154 cell communication
2.15 1.02e-09 GO:0007267 cell-cell signaling
1.42 4.74e-09 GO:0023052 signaling
2.15 8.22e-09 GO:0030182 neuron differentiation
2.02 9.02e-09 GO:0048699 generation of neurons
1.98 1.29e-08 GO:0022008 neurogenesis
1.73 1.61e-08 GO:0009653 anatomical structure morphogenesis
1.78 3.56e-08 GO:0051239 regulation of multicellular organismal process
1.28 8.13e-08 GO:0050896 response to stimulus
1.95 8.39e-08 GO:0006811 ion transport
2.69 2.96e-07 GO:0016337 cell-cell adhesion
1.90 3.09e-07 GO:0050793 regulation of developmental process
2.00 3.76e-07 GO:0007155 cell adhesion
2.00 3.76e-07 GO:0022610 biological adhesion
3.49 4.59e-07 GO:0045165 cell fate commitment
2.25 8.70e-07 GO:0019226 transmission of nerve impulse
2.25 8.70e-07 GO:0035637 multicellular organismal signaling
2.01 2.45e-06 GO:0045595 regulation of cell differentiation
1.95 2.70e-06 GO:2000026 regulation of multicellular organismal development
2.82 5.27e-06 GO:0007601 visual perception
2.82 5.27e-06 GO:0050953 sensory perception of light stimulus
2.11 5.84e-06 GO:0007186 G-protein coupled receptor protein signaling pathway
2.26 5.98e-06 GO:0007268 synaptic transmission
1.86 6.29e-06 GO:0009888 tissue development
1.82 9.68e-06 GO:0048468 cell development
3.21 7.71e-05 GO:0007156 homophilic cell adhesion
2.05 1.02e-04 GO:0007417 central nervous system development
1.94 3.45e-04 GO:0048666 neuron development
1.91 3.85e-04 GO:0009887 organ morphogenesis
2.38 5.06e-04 GO:0051960 regulation of nervous system development
2.25 6.46e-04 GO:0051093 negative regulation of developmental process
1.32 6.83e-04 GO:0007165 signal transduction
2.39 8.63e-04 GO:0045596 negative regulation of cell differentiation
2.42 1.31e-03 GO:0050767 regulation of neurogenesis
4.78 1.38e-03 GO:0048663 neuron fate commitment
1.46 1.63e-03 GO:0007166 cell surface receptor linked signaling pathway
1.71 1.83e-03 GO:0007600 sensory perception
4.15 1.92e-03 GO:0009582 detection of abiotic stimulus
2.96 2.17e-03 GO:0006814 sodium ion transport
2.12 2.34e-03 GO:0007420 brain development
1.92 3.15e-03 GO:0000904 cell morphogenesis involved in differentiation
1.16 4.21e-03 GO:0065007 biological regulation
1.91 4.75e-03 GO:0031175 neuron projection development
1.96 5.04e-03 GO:0048812 neuron projection morphogenesis
1.80 5.16e-03 GO:0048878 chemical homeostasis
2.15 5.92e-03 GO:0060284 regulation of cell development
1.96 6.60e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.88 8.29e-03 GO:0048858 cell projection morphogenesis
1.17 8.47e-03 GO:0050789 regulation of biological process
2.33 8.52e-03 GO:0048568 embryonic organ development
1.60 8.67e-03 GO:0032879 regulation of localization
1.73 9.14e-03 GO:0009790 embryo development
1.86 1.09e-02 GO:0032990 cell part morphogenesis
1.95 1.13e-02 GO:0007409 axonogenesis
1.78 1.19e-02 GO:0000902 cell morphogenesis
1.75 1.75e-02 GO:0032989 cellular component morphogenesis
2.09 2.05e-02 GO:0007610 behavior
1.24 2.13e-02 GO:0051716 cellular response to stimulus
5.88 2.21e-02 GO:0071248 cellular response to metal ion
3.43 2.79e-02 GO:0009581 detection of external stimulus
1.61 3.00e-02 GO:0040011 locomotion
1.82 3.54e-02 GO:0030001 metal ion transport
1.16 3.62e-02 GO:0050794 regulation of cellular process
5.01 3.69e-02 GO:0007602 phototransduction
2.52 4.26e-02 GO:0048562 embryonic organ morphogenesis
1.48 4.43e-02 GO:0002376 immune system process
4.47 4.74e-02 GO:0009583 detection of light stimulus
1.94 4.91e-02 GO:0048598 embryonic morphogenesis

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.84 2.06e-20 GO:0044459 plasma membrane part
1.54 8.05e-20 GO:0071944 cell periphery
1.54 1.26e-19 GO:0005886 plasma membrane
1.81 8.21e-18 GO:0005576 extracellular region
1.87 1.35e-11 GO:0031226 intrinsic to plasma membrane
1.86 6.32e-11 GO:0005887 integral to plasma membrane
1.33 1.64e-10 GO:0031224 intrinsic to membrane
3.76 4.38e-10 GO:0045211 postsynaptic membrane
1.89 1.16e-09 GO:0044421 extracellular region part
2.52 1.38e-09 GO:0045202 synapse
1.27 3.07e-09 GO:0044425 membrane part
1.31 3.93e-09 GO:0016021 integral to membrane
2.66 3.80e-08 GO:0044456 synapse part
2.07 2.20e-07 GO:0030054 cell junction
1.19 1.11e-05 GO:0016020 membrane
2.67 1.19e-05 GO:0034702 ion channel complex
1.76 6.05e-05 GO:0005615 extracellular space
2.76 7.36e-05 GO:0005882 intermediate filament
2.21 1.45e-04 GO:0005578 proteinaceous extracellular matrix
2.04 5.05e-04 GO:0031012 extracellular matrix
2.39 1.75e-03 GO:0045111 intermediate filament cytoskeleton
3.30 1.87e-03 GO:0045095 keratin filament
10.73 7.77e-03 GO:0005577 fibrinogen complex
2.56 8.98e-03 GO:0034703 cation channel complex
2.50 1.29e-02 GO:0009897 external side of plasma membrane
1.81 3.18e-02 GO:0009986 cell surface
1.77 4.84e-02 GO:0043005 neuron projection

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.29 3.82e-12 GO:0043565 sequence-specific DNA binding
1.68 1.34e-09 GO:0004872 receptor activity
2.52 2.18e-09 GO:0022838 substrate-specific channel activity
2.49 3.01e-09 GO:0015267 channel activity
2.48 3.38e-09 GO:0022803 passive transmembrane transporter activity
2.04 7.37e-09 GO:0015075 ion transmembrane transporter activity
2.49 9.41e-09 GO:0005216 ion channel activity
1.88 3.81e-08 GO:0022857 transmembrane transporter activity
1.90 8.59e-08 GO:0022891 substrate-specific transmembrane transporter activity
1.53 2.94e-07 GO:0004871 signal transducer activity
1.53 2.94e-07 GO:0060089 molecular transducer activity
1.80 5.27e-07 GO:0001071 nucleic acid binding transcription factor activity
1.80 5.27e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.66 2.26e-06 GO:0004888 transmembrane receptor activity
2.45 2.93e-06 GO:0022836 gated channel activity
1.67 3.81e-06 GO:0005215 transporter activity
1.69 2.29e-05 GO:0022892 substrate-specific transporter activity
3.97 8.76e-05 GO:0005230 extracellular ligand-gated ion channel activity
3.13 9.50e-05 GO:0015276 ligand-gated ion channel activity
3.13 9.50e-05 GO:0022834 ligand-gated channel activity
2.33 1.92e-04 GO:0005261 cation channel activity
2.86 2.23e-04 GO:0008509 anion transmembrane transporter activity
1.61 6.04e-04 GO:0030528 transcription regulator activity
1.82 1.10e-03 GO:0008324 cation transmembrane transporter activity
3.23 1.43e-03 GO:0015081 sodium ion transmembrane transporter activity
1.62 4.84e-03 GO:0004930 G-protein coupled receptor activity
3.32 5.52e-03 GO:0005262 calcium channel activity
3.83 1.20e-02 GO:0003707 steroid hormone receptor activity
2.45 2.22e-02 GO:0046873 metal ion transmembrane transporter activity
3.62 2.31e-02 GO:0004879 ligand-dependent nuclear receptor activity
1.50 2.77e-02 GO:0005102 receptor binding
1.63 2.85e-02 GO:0005509 calcium ion binding
2.43 3.62e-02 GO:0022843 voltage-gated cation channel activity
5.23 4.28e-02 GO:0001608 nucleotide receptor activity, G-protein coupled
5.23 4.28e-02 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled